Active Pharmaceutical Ingredients - Dr Reddy's
Active Pharmaceutical Ingredients - Dr Reddy's

About Dapagliflozin (Propanediol Monohydrate) API

Product
  • Therapeutic Category Anti-Diabético

  • CAS Number

    461432-26-8

  • API Technology

    Synthetic

  • Dose Form

    Tablets

  • Dr Reddy's Development Status

    Available

  • Available Regulatory Filing

    Singapore DMF, Europe (CEP), USDMF, Taiwan DMF

Mechanism of Action

Sodium-glucose cotransporter 2 (SGLT2), expressed in the proximal renal tubules, is responsible for the majority of the reabsorption of filtered glucose from the tubular lumen. Dapagliflozin is an inhibitor of SGLT2. By inhibiting SGLT2, dapagliflozin reduces reabsorption of filtered glucose and lowers the renal threshold for glucose, and thereby increases urinary glucose excretion

Indication

FARXIGA is a sodium-glucose cotransporter 2 (SGLT2) inhibitor indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus.

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