Active Pharmaceutical Ingredients - Dr Reddy's
Active Pharmaceutical Ingredients - Dr Reddy's

About Venetoclax API

Product
  • Therapeutic Category Oncology

  • CAS Number

    1257044-40-8

  • API Technology

    High Potent

  • Dose Form

    Oral Solid/Tablets

  • Dr Reddy's Development Status

    Available

  • Available Regulatory Filing

    USDMF

Mechanism of Action

Venetoclax is a selective and orally bioavailable small-molecule inhibitor of BCL-2, an antiapoptotic protein. Overexpression of BCL-2 has been demonstrated in CLL cells where it mediates tumor cell survival and has been associated with resistance to chemotherapeutics. Venetoclax helps restore the process of apoptosis by binding directly to the BCL-2 protein, displacing pro-apoptotic proteins like BIM, triggering mitochondrial outer membrane permeabilization and the activation of caspases. In nonclinical studies, venetoclax has demonstrated cytotoxic activity in tumor cells that overexpress BCL-2.

Indication

VENCLEXTA is a BCL-2 inhibitor indicated for the treatment of patients with chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL), with or without 17p deletion, who have received at least one prior therapy.

Request for Quotation

Get in touch with us by filling out the form below. Our team will reach out to you shortly!

Phone
Country *
Select Product *
Select Regulatory Requirements
Select Purpose

Related APIs

ゾレドロン酸

Oncology

arrow

ダサチニブ一水和物

Oncology

arrow

アダグラシブ

Oncology

arrow

ベンダムスチン塩酸塩

Oncology

arrow

フルキンチニブ

Oncology

arrow

ベネトクラクス

Oncology

arrow

ツカチニブ

Oncology

arrow

リプレチニブ

Oncology

arrow

アビラテロン酢酸エステル

Oncology

arrow

アザシチジン

Oncology

arrow

ボルテゾミブ

Oncology

arrow

カバジタキセル

Oncology

arrow

カボザンチニブ塩酸塩

Oncology

arrow

カボザンチニブS-リンゴ酸塩

Oncology

arrow

カペシタビン

Oncology

arrow

カルフィルゾミブ

Oncology

arrow

デシタビン

Oncology

arrow

デュクラバシチニブ

Oncology

arrow

アパルタミド(非晶質およ びB型)

Oncology

arrow

エリブリンメシル酸塩

Oncology

arrow

ゲムシタビン

Oncology

arrow

ロムスチン

Oncology

arrow

ニロチニブ塩酸塩

Oncology

arrow

オラパリブ( A型)

Oncology

arrow

パルボシクリブ(A型)

Oncology

arrow

パゾパニブ

Oncology

arrow

ペメトレキセド二ナトリウム七水和物

Oncology

arrow

ピルトブルチニブ

Oncology

arrow

レルゴリクス

Oncology

arrow

ポマリドミド

Oncology

arrow

アカラブルチニブ

Oncology

arrow

Capivasertib(卡帕塞替尼)

Oncology

arrow

レナリドミド( A型)

Oncology

arrow

ミドスタウリン(非晶質お よびII型)

Oncology

arrow

レンバチニブメシ ル酸塩(C型およびMIBK溶媒和物)

Oncology

arrow

エンザルタミド(結晶およびプレミックス)

Oncology

arrow

FAQs

What are the uses of Venetoclax API?
  • Treats chronic lymphocytic leukemia (CLL), small lymphocytic lymphoma (SLL), and acute myeloid leukemia (AML)

How do you store Venetoclax API?
  • Store in original container at or below 30°C (86°F), protect from moisture

What are the precautions to take while using Venetoclax API?
  • Avoid live vaccines
    Monitor for tumor lysis syndrome (TLS)
    Ensure adequate hydration

What is the dosage form and strength currently available for Venetoclax?
  • Available as oral tablets: 10 mg, 50 mg, 100 mg

免責事項

No information on this website, including any reference to any product or service constitutes an offer for sale or be construed as representing an offer for sale. Products protected under valid patents are not offered or supplied for commercial use. However, in certain cases, at Dr. Reddy's sole discretion, and subject to local legal requirement, the research quantities of such products may be offered for the purpose of regulatory submissions under Section 107A of the Indian Patent Act (Bolar exemption), wherever such regulatory exemptions exist. The buyers should make their independent evaluation of the product or service including, patent scenario in their respective markets and will be responsible for all patent related liabilities Dr. Reddy's disclaims all warranties, express or implied, including but not limited to warranties of merchantability, fitness for a particular purpose and non-infringement.

Disclaimer: Products under patent(s) are offered only for R&D purposes U/S 107A of the Patent Act (Bolar Exemption) and not for commercial sale.
ベネトクラックスAPIメーカーとサプライヤー | CAS 1257044-40-8 - Dr. Reddy's