About Dapagliflozin (Amorphous) API
Therapeutic CategoryAnti-Diabetic

CAS Number
461432-26-8
API Technology
Synthetic
Dose Form
Oral Solids
Dr Reddy's Development Status
Available
Available Regulatory Filing
USDMF, Brazil DMF, EUDMF, Canada DMF, Korea DMF, Russia DMF
Mechanism of Action
Sodium-glucose cotransporter 2 (SGLT2), expressed in the proximal renal tubules, is responsible for the majority of the reabsorption of filtered glucose from the tubular lumen. Dapagliflozin is an inhibitor of SGLT2. By inhibiting SGLT2, dapagliflozin reduces reabsorption of filtered glucose and lowers the renal threshold for glucose, and thereby increases urinary glucose excretion
Indication
FARXIGA is a sodium-glucose cotransporter 2 (SGLT2) inhibitor indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus.
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FAQs
Dapagliflozin Amorphous API is used to treat type 2 diabetes, chronic kidney disease, and heart failure.
Lowers blood glucose, promotes weight loss, reduces blood pressure, and decreases cardiovascular risks.
Handle with care, avoid inhalation, ingestion, and contact with eyes and skin. Use protective equipment.
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