About Gatifloxacin (Anhydrous) API
Therapeutic CategoryAnti-Infective
CAS Number
112811-59-3
API Technology
Synthetic
Dose Form
Opthalmic
Dr Reddy's Development Status
Available
Available Regulatory Filing
Brazil DMF, USDMF
Mechanism of Action
Gatifloxacin is a quinolone antimicrobial drug
Gatifloxacin is an 8-methoxyfluoroquinolone with a 3-methylpiperazinyl substituent at C7. The antibacterial action of gatifloxacin results from inhibition of DNA gyrase and topoisomerase IV. DNA gyrase is an essential enzyme that is involved in the replication, transcription and repair of bacterial DNA. Topoisomerase IV is an enzyme known to play a key role in the partitioning of the chromosomal DNA during bacterial cell division.
Indication
ZYMAR® is a quinolone antimicrobial indicated for the treatment of bacterial conjunctivitis caused by susceptible strains of the following organisms:
Haemophilus influenzae, Corynebacterium propinquum, Staphylococcus aureus, Staphylococcus epidermidis, Streptococcus mitis group, Streptococcus pneumoniae
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