Fruquintinib

Mechanism of Action

Fruquintinib is a tyrosine kinase inhibitor (TKI) that works by blocking the activity of specific enzymes, known as tyrosine kinases, which are involved in the growth and spread of cancer cells.

In particular, fruquintinib targets vascular endothelial growth factor receptors (VEGFRs), which play a crucial role in the development of blood vessels that support the growth of tumors. By inhibiting the activity of VEGFRs, fruquintinib slows down the growth of new blood vessels and restricts the blood supply to the tumor, ultimately reducing its size and slowing its progression.

Fruquintinib has been approved in China for the treatment of certain types of advanced or metastatic colorectal cancer, and it is being studied in clinical trials for its efficacy and safety in treating other types of cancer, such as non-small cell lung cancer, gastric cancer, and breast cancer.

Indication

Fruquintinib is indicated for the treatment of advanced or metastatic colorectal cancer in China. The drug is intended for patients who have received previous treatment with other chemotherapy drugs and have not responded or have stopped responding to those treatments.

It is important to note that fruquintinib is still being studied in clinical trials for its efficacy and safety in treating other types of cancer, such as non-small cell lung cancer, gastric cancer, and breast cancer. The approval status and indications for fruquintinib may vary depending on the country and the regulatory agencies involved.

Dr. Reddy’sの専門知識・技術

ハイデラバード（インド）に本社を構えるDr. Reddy’s Laboratoriesは、世界的に有名な原薬（API）供給業者です。Dr. Reddy’sのAPIビジネスは米国、ヨーロッパ、ブラジル、南米、日本、中国、韓国、その他の新興市場において製薬会社の推奨パートナーとなっています。

Dr. Reddy’sのAPIビジネスは、ステロイド、ペプチド、複合長鎖分子、高薬理活性API（HPAPI /腫瘍学薬）など、複合APIの開発・製造において、30年以上にわたり高度な技術的実績を築き上げ、成長しています。この専門知識・技術は弊社の知的財産および規制関連業務の実績と共に、一貫して規制基準を満たし、それを超える優れた価値を生み出しています。Dr. Reddyの(-) API, R&D (研究開発)、IP、規制の高度な専門知識・技能の結果です。

顧客が真っ先に市場に参入するのに重要な要素は、機敏な供給網です。弊社は全施設を効率的に、そしてコストを最適化して稼働させ、品質と安全性、また、生産性の最新基準に従うことで、そうした供給網を実現させます。オフィスと工場の結びつきを強化し、ダイナミックな市場の変化に迅速に対応しています。そうした理由から、弊社は不足を解消して突発的な供給を満たすことができるのです。