About Tizanidine Hydrochloride API
Therapeutic CategoryCentral Nervous System (CNS)
CAS Number
64461-82-1
API Technology
Synthetic
Dose Form
Capsule/ Tablet
Dr Reddy's Development Status
Available
Available Regulatory Filing
USDMF, CEP Submitted, EUDMF
Mechanism of Action
Tizanidine is a central alpha-2-adrenergic receptor agonist and presumably reduces spasticity by increasing presynaptic inhibition of motor neurons. The effects of tizanidine are greatest on polysynaptic pathways. The overall effect of these actions is thought to reduce facilitation of spinal motor neurons.
Indication
Zanaflex is a central alpha-2-adrenergic agonist indicated for the management of spasticity
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