CAS Number: 64461-82-1
Tizanidine is a central alpha-2-adrenergic receptor agonist and presumably reduces spasticity by increasing presynaptic inhibition of motor neurons. The effects of tizanidine are greatest on polysynaptic pathways. The overall effect of these actions is thought to reduce facilitation of spinal motor neurons.
Zanaflex is a central alpha-2-adrenergic agonist indicated for the management of spasticity
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