About Risperidone API
Therapeutic CategoryCentral Nervous System (CNS)
API Technology
Synthetic
Dose Form
Injectable, Solution/Tablet
Dr Reddy's Development Status
Available
Available Regulatory Filing
USDMF, CEP Submitted, Brazil DMF, Japan DMF, Korea DMF
Mechanism of Action
The mechanism of action of risperidone in schizophrenia is unclear. The drug’s therapeutic activity in schizophrenia could be mediated through a combination of dopamine Type 2 (D2) and serotonin Type 2 (5HT2) receptor antagonism. The clinical effect from risperidone results from the combined concentrations of risperidone and its major active metabolite, 9hydroxyrisperidone (paliperidone). Antagonism at receptors other than D2 and 5HT2 may explain some of the other effects of risperidone
Indication
RISPERDAL CONSTA® is an atypical antipsychotic indicated:
- For the treatment of schizophrenia.
- As monotherapy or as adjunctive therapy to lithium or valproate for the maintenance treatment of Bipolar I Disorder.
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