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伏环孢素

伏环孢素-API

伏环孢素 API

CAS Number: 515814-01-4

About 伏环孢素 API

Therapeutic Category
Nephorology

API Technology
Synthetic

Dose Form
Oral Solid/Capsules

Dr Reddy's Development Status
Under-Development

作用机制

Voclosporin is an immunosuppressant drug that works by inhibiting the activity of an enzyme called calcineurin. Calcineurin is involved in the activation of T cells, which are a type of white blood cell that play a key role in the immune system.

In individuals with autoimmune diseases such as lupus nephritis, the immune system mistakenly attacks healthy tissues and organs, causing inflammation and damage. Voclosporin works by blocking calcineurin and therefore inhibiting the activation of T cells, which helps to reduce the inflammation and prevent tissue damage.

In addition to its immunosuppressive effects, voclosporin has also been shown to have antiproliferative and anti-inflammatory effects, which may contribute to its ability to improve outcomes in patients with lupus nephritis.

It is important to note that while voclosporin can be effective in controlling the symptoms of autoimmune diseases, it can also suppress the immune system, making patients more susceptible to infections. As with any medication, the benefits and risks of voclosporin should be carefully weighed by a healthcare provider before it is prescribed.

适应症

Voclosporin is indicated for the treatment of certain autoimmune diseases, specifically for the treatment of lupus nephritis. Lupus nephritis is a type of kidney disease that occurs in people with systemic lupus erythematosus (SLE), a chronic autoimmune disease in which the body's immune system attacks its own tissues and organs.

Voclosporin is used in combination with another immunosuppressant, mycophenolate mofetil, to improve kidney function and reduce the risk of kidney failure in patients with lupus nephritis.

It is important to note that the safety and effectiveness of voclosporin may vary depending on individual circumstances and that patients should consult their healthcare provider to determine if voclosporin is appropriate for their treatment. Additionally, patients taking voclosporin may require monitoring for potential side effects and drug interactions.

Dr. Reddy's的专长

Dr. Reddy's总部位于印度海得拉巴,是全球领先的活性药物成分(API)供应商之一。 Dr. Reddy's的API业务是美国、欧洲、巴西、拉丁美洲、日本、中国、韩国和新兴市场的制药公司的首选合作伙伴。

Dr. Reddy's博士的API业务在过去30多年来在开发和制造复杂API(如类固醇,多肽,复杂长链分子和高效API(HPAPI /肿瘤药物))方面所建立的深厚技术优势中茁壮成长。 我们在知识产权和法规事务方面的实力可以帮助我们始终如一地达到并超越监管标准,从而为这一专业知识提供补充。 Dr. Reddy's博士 伏环孢素 API是研发,知识产权和监管方面广泛专业知识的结果。

帮助我们的客户率先进入市场的关键组成部分是响应式供应链。 我们通过确保所有设施都高效运行并达到最新的质量,安全和生产率标准来实现这一目标。 业务和工厂之间的强大互联可以快速响应动态的市场变化,从而避免短缺并满足需求的突然激增。

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免责声明

本目錄中的任何信息(包括對任何產品或服務的任何引用)均不構成銷售要約,或被解釋為代表銷售要約。受有效專利保護的產品不提供或供應用於商業用途。但是,只要存在此類監管豁免,就可以出於監管提交的目的提供此類產品的研究數量。買方應對各自市場的專利方案進行獨立評估,並承擔所有與專利相關的責任。在印度受有效專利保護的產品不可用於商業用途,但可用於第 107A 節。

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免责声明

本目錄中的任何信息(包括對任何產品或服務的任何引用)均不構成銷售要約,或被解釋為代表銷售要約。受有效專利保護的產品不提供或供應用於商業用途。但是,只要存在此類監管豁免,就可以出於監管提交的目的提供此類產品的研究數量。買方應對各自市場的專利方案進行獨立評估,並承擔所有與專利相關的責任。在印度受有效專利保護的產品不可用於商業用途,但可用於第 107A 節。