About Apremilast (Amorphous & Form B) API
Therapeutic CategoryCentral Nervous System (CNS)
CAS Number
608141-41-9
API Technology
Synthetic
Dose Form
Oral Solid/Tablets
Dr Reddy's Development Status
Available
Available Regulatory Filing
USDMF, Brazil DMF, Canada DMF
Mechanism of Action
Apremilast is an oral small-molecule inhibitor of phosphodiesterase 4 (PDE4) specific for cyclic adenosine monophosphate (cAMP). PDE4 inhibition results in increased intracellular cAMP levels. The specific mechanism(s) by which apremilast exerts its therapeutic action in psoriatic arthritis patients and psoriasis patients is not well defined.
Indication
OTEZLA, an inhibitor of phosphodiesterase 4 (PDE4), is indicated for the treatment of:
- Adult patients with active psoriatic arthritis
- Patients with moderate to severe plaque psoriasis who are candidates for phototherapy or systemic therapy
Related APIs
Atomoxetine Hydrochloride
Central Nervous System (CNS)
Benztropine Mesylate
Central Nervous System (CNS)
Dimethyl Fumarate
Central Nervous System (CNS)
Edaravone
Central Nervous System (CNS)
Eslicarbazepine Acetate
Central Nervous System (CNS)
Eszopiclone
Central Nervous System (CNS)
Levetiracetam
Central Nervous System (CNS)
Lumateperone Tosylate
Central Nervous System (CNS)
Lurasidone Hydrochloride
Central Nervous System (CNS)
Memantine Hydrochloride
Central Nervous System (CNS)
Pregabalin
Central Nervous System (CNS)
Rimegepant
Central Nervous System (CNS)
Risperidone
Central Nervous System (CNS)
Rivastigmine Hydrogen Tartrate
Central Nervous System (CNS)
Ropinirole Hydrochloride
Central Nervous System (CNS)
Sugammadex Sodium
Central Nervous System (CNS)
Tizanidine Hydrochloride
Central Nervous System (CNS)
Xanomeline
Central Nervous System (CNS)
Fluoxetine
Central Nervous System (CNS)
Quetiapine Fumarate
Central Nervous System (CNS)
Apremilast (form B)
Central Nervous System (CNS)
Donepezil Hydrochloride
Central Nervous System (CNS)
Siponimod Hemifumarate
Central Nervous System (CNS)
Ziprasidone Hydrochloride Anhydrous
Central Nervous System (CNS)
Request for Quotation
Get in touch with us by filling out the form below. Our team will reach out to you shortly!
Related Resources
FAQs
Available in Tablet dosage form with a strength of 10, 20 and 30 Mg
-
Store below 30°C (86°F).
-
Apremilast is used to treat ulcers in the mouth in people with Behcet's syndrome (a disorder that causes blood vessel swelling in the body). Apremilast is in a class of medications called phosphodiesterase inhibitors. It works by blocking the action of certain natural substances in the body that cause inflammation.
-
Due to its low solubility and permeability, it is classified as a class IV drug according to BCS classification.
-
We offer Amorphous and crystalline form
Disclaimer
No information on this website, including any reference to any product or service constitutes an offer for sale or be construed as representing an offer for sale. Products protected under valid patents are not offered or supplied for commercial use. However, in certain cases, at Dr. Reddy's sole discretion, and subject to local legal requirement, the research quantities of such products may be offered for the purpose of regulatory submissions under Section 107A of the Indian Patent Act (Bolar exemption), wherever such regulatory exemptions exist. The buyers should make their independent evaluation of the product or service including, patent scenario in their respective markets and will be responsible for all patent related liabilities Dr. Reddy's disclaims all warranties, express or implied, including but not limited to warranties of merchantability, fitness for a particular purpose and non-infringement.