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About Vonoprazan Fumarate API

Product
  • Therapeutic Category胃肠道 – GI

  • API Technology

    Small molecule

  • Dose Form

    Oral Solid/Tablets

  • Dr Reddy's Development Status

    Available (Commercial)

  • Available Regulatory Filing

    USDMF, Brazil DMF

作用机制

Vonoprazan fumarate is a proton pump inhibitor that works by reducing the amount of acid produced in the stomach. It does this by blocking the activity of the enzyme H+/K+ ATPase, which is responsible for producing gastric acid.

The mechanism of action of vonoprazan fumarate involves the inhibition of the final step of acid secretion, which is the transport of hydrogen ions into the gastric lumen. This leads to a decrease in the production of gastric acid and therefore reduces the amount of acid that is available to cause damage to the esophagus, stomach, or duodenum.

Vonoprazan fumarate has a rapid onset of action and provides sustained acid suppression for 24 hours with a single daily dose, making it an effective treatment for a variety of acid-related conditions such as gastroesophageal reflux disease (GERD), peptic ulcer disease (PUD), and Zollinger-Ellison syndrome.

适应症

Vonoprazan fumarate is indicated for the treatment of various acid-related conditions, including:

Gastroesophageal Reflux Disease (GERD): Vonoprazan fumarate is used to relieve symptoms of GERD, such as heartburn, regurgitation, and chest pain.

Peptic Ulcer Disease (PUD): Vonoprazan fumarate is used to treat PUD, which is caused by the formation of sores or ulcers in the stomach or duodenum.

Zollinger-Ellison Syndrome: Vonoprazan fumarate is used to treat Zollinger-Ellison syndrome, a rare condition in which the stomach produces too much acid.

It is important to note that vonoprazan fumarate should be used only under the supervision of a healthcare provider, and the dose and duration of treatment should be based on the individual's medical condition and response to therapy.

Dr. Reddy's的专长

Dr. Reddy's总部位于印度海得拉巴,是全球领先的活性药物成分(API)供应商之一。 Dr. Reddy's的API业务是美国、欧洲、巴西、拉丁美洲、日本、中国、韩国和新兴市场的制药公司的首选合作伙伴。

Dr. Reddy's博士的API业务在过去30多年来在开发和制造复杂API(如类固醇,多肽,复杂长链分子和高效API(HPAPI /肿瘤药物))方面所建立的深厚技术优势中茁壮成长。 我们在知识产权和法规事务方面的实力可以帮助我们始终如一地达到并超越监管标准,从而为这一专业知识提供补充。 Dr. Reddy's博士 富马酸伏诺拉生 API是研发,知识产权和监管方面广泛专业知识的结果。

帮助我们的客户率先进入市场的关键组成部分是响应式供应链。 我们通过确保所有设施都高效运行并达到最新的质量,安全和生产率标准来实现这一目标。 业务和工厂之间的强大互联可以快速响应动态的市场变化,从而避免短缺并满足需求的突然激增。

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FAQs

What is Vonoprazan Fumarate API used for?
  • Treats erosive esophagitis, GERD, and peptic ulcers
    Used with antibiotics for Helicobacter pylori eradication

What is the dosage form and strength currently available for Vonoprazan Fumarate?
  • Available as oral tablets: 10 mg, 20 mg

What are the benefits of Vonoprazan Fumarate API?
  • Potent acid suppression
    Rapid symptom relief
    Effective in H. pylori eradication
     

How do you store Vonoprazan Fumarate API?
  • Store at 20°C to 25°C (68°F to 77°F), protect from moisture and light

Disclaimer: Products under patent(s) are offered only for R&D purposes U/S 107A of the Patent Act (Bolar Exemption) and not for commercial sale.