Active Pharmaceutical Ingredients - Dr Reddy's
Active Pharmaceutical Ingredients - Dr Reddy's

About Dimethyl Fumarate API

Product
  • Categoría Terapéutica Sistema Nervioso Central (SNC)

  • Número CAS

    624-49-7

  • Tecnología del API

    Sintética

  • Forma de Dosificación

    Sólido Oral/Cápsulas

  • Estado de Desarrollo en Dr. Reddy’s

    Disponible

  • Presentación Regulatoria Disponible

    USDMF, EUDMF, DMF de Brasil, DMF de China

Mechanism of Action

The mechanism by which dimethyl fumarate (DMF) exerts its therapeutic effect in multiple sclerosis is unknown. DMF and the metabolite, monomethyl fumarate (MMF), have been shown to activate the Nuclear factor (erythroid-derived 2)-like 2 (Nrf2) pathway in vitro and in vivo in animals and humans. The Nrf2 pathway is involved in the cellular response to oxidative stress. MMF has been identified as a nicotinic acid receptor agonist in vitro.

Indication

TECFIDERA is indicated for the treatment of patients with relapsing forms of multiple sclerosis

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FAQs

How do you store Dimethyl Fumarate API?
  • Store at temperature  2 – 8°C

What is the use of Dimethyl Fumarate?
  • Dimethyl fumarate is used to treat adults with relapsing forms of multiple sclerosis

What precautions need to be taken while having Dimethyl Fumarate?
  • Avoid being near people who are sick or have infections while you are using this medicine.

What is the dosage form available for Dimethyl Fumarate API ?
  • Dimethyl fumarate is available in capsule dosage form with 120 and 240 mg

What polymorph form is available for Dimethyl fumarate?
  • We offer Crystalline Form of Dimethyl Fumarate

What is the BCS classification for Dimethyl fumarate?

Descargo de responsabilidad

No information on this website, including any reference to any product or service constitutes an offer for sale or be construed as representing an offer for sale. Products protected under valid patents are not offered or supplied for commercial use. However, in certain cases, at Dr. Reddy's sole discretion, and subject to local legal requirement, the research quantities of such products may be offered for the purpose of regulatory submissions under Section 107A of the Indian Patent Act (Bolar exemption), wherever such regulatory exemptions exist. The buyers should make their independent evaluation of the product or service including, patent scenario in their respective markets and will be responsible for all patent related liabilities Dr. Reddy's disclaims all warranties, express or implied, including but not limited to warranties of merchantability, fitness for a particular purpose and non-infringement.

Disclaimer: Products under patent(s) are offered only for R&D purposes U/S 107A of the Patent Act (Bolar Exemption) and not for commercial sale.