Mechanism of Action

Doxazosin is a quinazoline derivative that acts as a competitive alpha1-antagonist at the post-synaptic receptor. Doxazosin competitively inhibits post-synaptic alpha1-adrenergic receptors causing vasodilation of arterioles and veins, which results in decreased total peripheral resistance and blood pressure

Indication

Doxazosin belongs to a group of medicines called alpha blockers. It's used to treat high blood pressure (hypertension) and symptoms of an enlarged prostate (benign prostatic enlargement).