About Metoprolol Succinate API
Therapeutic CategoryCardiovascular
CAS Number
98418-47-4
API Technology
Synthetic
Dose Form
Oral Solid/Tablets
Dr Reddy's Development Status
Available
Available Regulatory Filing
USDMF, CEP Submitted, Brazil DMF, Canada DMF, China DMF
Mechanism of Action
Several possible mechanisms have been proposed:
- Competitive antagonism of catecholamine at peripheral (especially cardiac) adrenergic neuron sites, leading to decreased cardiac output;
- A central effect leading to reduced sympathetic outflow to the periphery; and
- Suppression of renin activity.
Indication
- Hypertension, to lower blood pressure. Lowering blood pressure reduces the risk of fatal and non-fatal cardiovascular events, primarily strokes and myocardial infarctions.
- Angina Pectoris.
- Heart Failure - for the treatment of stable, symptomatic (NYHA Class II or III) heart failure of ischemic, hypertensive, or cardiomyopathic origin.
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FAQs
Treats hypertension (high blood pressure)
Manages angina (chest pain)
Reduces risk of heart failure hospitalization
-
Avoid abrupt discontinuation
Inform doctor of any respiratory issues, diabetes, or liver disease
Avoid driving until you know its effects
-
Lowers blood pressure
Reduces chest pain frequency
Improves survival rates in heart failure patients
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