About Palbociclib API
Therapeutic Category Oncology
CAS Number
571190-30-2
API Technology
Synthetic
Dose Form
Capsule/ Tablet
Dr Reddy's Development Status
Available
Available Regulatory Filing
Brazil DMF, USDMF, Singapore DMF, Australia DMF, Canada DMF, Taiwan DMF
Mechanism of Action
It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6.
Indication
IBRANCE is a kinase inhibitor indicated for the treatment of hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative advanced or metastatic breast cancer in combination with:
- An aromatase inhibitor as initial endocrine based therapy in postmenopausal women; or
- Fulvestrant in women with disease progression following endocrine therapy.
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FAQs
Treats HR-positive, HER2-negative advanced or metastatic breast cancer.
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Available as oral tablets: 75 mg, 100 mg, 125 mg.
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Store at 20°C to 25°C (68°F to 77°F), with excursions permitted between 15°C to 30°C (59°F to 86°F).