About Apixaban API
Therapeutic CategoryCardiovascular
CAS Number
503612-47-3
API Technology
Synthetic
Dose Form
Oral Solid/Tablets
Dr Reddy's Development Status
Available
Available Regulatory Filing
USDMF, Brazil DMF, Canada DMF, Korea DMF, China DMF
Mechanism of Action
Apixaban is a selective inhibitor of FXa. It does not require antithrombin III for antithrombotic activity. Apixaban inhibits free and clot-bound FXa, and prothrombinase activity. Apixaban has no direct effect on platelet aggregation, but indirectly inhibits platelet aggregation induced by thrombin. By inhibiting FXa, apixaban decreases thrombin generation and thrombus development
Indication
ELIQUIS is a factor Xa inhibitor indicated:
- To reduce the risk of stroke and systemic embolism in patients with nonvalvular atrial fibrillation.
- For the prophylaxis of deep vein thrombosis (DVT), which may lead to pulmonary embolism (PE), in patients who have undergone hip or knee replacement surgery.
- For the treatment of DVT and PE, and for the reduction in the risk of recurrent DVT and PE following initial therapy.
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FAQs
Available in Tablet dosage/film coated form with a strength of 2.5 and 5 Mg
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Apixaban belongs to class 3 of BCS classification.
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Store at 20 °C to 25 °C (68 °F-77 °F); excursions permitted between 15 °C and 30 °C
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Apixaban is an anticoagulant used for the prophylaxis of stroke and systemic embolism in nonvalvular atrial fibrillation, and deep vein thrombosis(DVT) leading to pulmonary embolism(PE), including in patients after a hip or knee replacement surgery.
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It is important to avoid foods such as grapefruit and other medications that can increase your risk of bleeding while taking this medication.
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We offer crystalline Form
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Apixaban is a medicine use to prevent blood clots
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