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About Rivaroxaban API

Product
  • Therapeutic CategoryCardiovascular

  • CAS Number

    366789-02-8

  • API Technology

    Synthetic

  • Dose Form

    Oral Solid/Tablets

  • Dr Reddy's Development Status

    Available

  • Available Regulatory Filing

    USDMF, CEP Submitted, Brazil DMF, Canada DMF, Russia DMF

Mechanism of Action

XARELTO is a selective inhibitor of FXa. It does not require a cofactor (such as Anti-thrombin III) for activity. Rivaroxaban inhibits free FXa and prothrombinase activity. Rivaroxaban has no direct effect on platelet aggregation, but indirectly inhibits platelet aggregation induced by thrombin. By inhibiting FXa, rivaroxaban decreases thrombin generation.

Indication

XARELTO is a factor Xa inhibitor indicated:

  • To reduce the risk of stroke and systemic embolism in patients with nonvalvular atrial fibrillation
  • For the treatment of deep vein thrombosis (DVT)
  • For the treatment of pulmonary embolism (PE)  
  • For the reduction in the risk of recurrence of DVT and/or PE in patients at continued risk for recurrent DVT and/or PE after completion of initial treatment lasting at least 6 months  
  • For the prophylaxis of DVT, which may lead to PE in patients undergoing knee or hip replacement surgery

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Related Resources

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FAQs

What is RIVAROXABAN API used to treat?
  • It is a cardiovascular drug used to treat Nonvalvular atrial fibrillation, deep vein thrombosis, pulmonary embolism.


     

What is the safety guide for RIVAROXABAN API?
  • The safety dose for Rivaroxaban is 2.5, 10, 15 & 20 mg

What should you check before administering RIVAROXABAN API?
  • Circulating levels of rivaroxaban based on its anticoagulant action.

What are offerings of Dr. Reddy's for RIVAROXABAN API?
  • We offer Form-I of Rivaroxaban API

What is the process available for ordering RIVAROXABAN API?

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Disclaimer: Products under patent(s) are offered only for R&D purposes U/S 107A of the Patent Act (Bolar Exemption) and not for commercial sale.