Tucatinib

作用机制

Tucatinib is a small molecule tyrosine kinase inhibitor (TKI) that works by blocking the activity of specific protein kinases involved in cancer cell proliferation and survival.

Tucatinib is a small molecule tyrosine kinase inhibitor (TKI) that works by blocking the activity of specific Tucatinib specifically targets the HER2 (human epidermal growth factor receptor 2) protein, which is often over-expressed in certain types of breast and gastric cancers. By blocking the activity of HER2, tucatinib inhibits the signaling pathways that drive cancer cell growth and survival, leading to cancer cell death.

Tucatinib has been approved by the US Food and Drug Administration (FDA) for the treatment of advanced HER2-positive breast cancer in combination with capecitabine and trastuzumab.

适应症

Tucatinib is a small molecule inhibitor of the HER2 protein and is indicated for the treatment of certain types of cancer. Specifically, it is approved for the treatment of advanced unresectable or metastatic HER2-positive breast cancer in combination with trastuzumab and capecitabine for adult patients who have received one or more prior anti-HER2-based regimens.

Tucatinib has shown to significantly improve progression-free survival compared to treatment with trastuzumab and capecitabine alone in clinical trials. However, it is important to note that the safety and effectiveness of tucatinib may vary depending on individual circumstances and that patients should consult their healthcare provider to determine if tucatinib is appropriate for their treatment.

Dr. Reddy's的专长

Dr. Reddy's总部位于印度海得拉巴，是全球领先的活性药物成分（API）供应商之一。 Dr. Reddy's的API业务是美国、欧洲、巴西、拉丁美洲、日本、中国、韩国和新兴市场的制药公司的首选合作伙伴。

Dr. Reddy's博士的API业务在过去30多年来在开发和制造复杂API（如类固醇，多肽，复杂长链分子和高效API（HPAPI /肿瘤药物））方面所建立的深厚技术优势中茁壮成长。 我们在知识产权和法规事务方面的实力可以帮助我们始终如一地达到并超越监管标准，从而为这一专业知识提供补充。 Dr. Reddy's博士 Tucatinib API是研发，知识产权和监管方面广泛专业知识的结果。

帮助我们的客户率先进入市场的关键组成部分是响应式供应链。 我们通过确保所有设施都高效运行并达到最新的质量，安全和生产率标准来实现这一目标。 业务和工厂之间的强大互联可以快速响应动态的市场变化，从而避免短缺并满足需求的突然激增。