Treprostinil Diolamine

Mechanism of Action

Treprostinil diolamine is a prostacyclin analogue that is used as a medication for the treatment of pulmonary arterial hypertension (PAH) and other forms of cardiovascular disease.

The mechanism of action of treprostinil diolamine is to increase the levels of prostacyclin, a potent vasodilator, in the blood. Prostacyclin acts on the cells that line the blood vessels to relax the smooth muscle and increase blood flow, which helps to improve the symptoms of PAH and other forms of cardiovascular disease.

Additionally, treprostinil diolamine has anti-proliferative and anti-inflammatory effects that help to slow the progression of PAH. It also reduces the formation of blood clots, which is important for preventing serious complications associated with cardiovascular disease.

Indication

Treprostinil diolamine is a medication that is used for the treatment of pulmonary arterial hypertension (PAH) and other forms of cardiovascular disease.

The indications for treprostinil diolamine include:

Pulmonary Arterial Hypertension (PAH): Treprostinil diolamine is used for the treatment of PAH, a serious condition in which the blood pressure in the pulmonary arteries is elevated, leading to difficulty breathing and other symptoms.

Digital Ulcers in Systemic Sclerosis: Treprostinil diolamine is used to treat digital ulcers in patients with systemic sclerosis, a disease that causes thickening and hardening of the skin and connective tissues.

Chronic Thromboembolic Pulmonary Hypertension (CTEPH): Treprostinil diolamine is used as a treatment option for CTEPH, a type of pulmonary hypertension that occurs after a blood clot has formed in the lungs.

Dr. Reddy's Expertise

Headquartered in Hyderabad, India, Dr. Reddy's Laboratories is one of the leading Active Pharmaceutical Ingredients (API) manufacturers and suppliers globally for Treprostinil Diolamine API. Dr. Reddy's API business is a preferred partner to pharma companies across the US, Europe, Brazil, Latin America, Japan, China, Korea, Middle East and other emerging markets.

Dr. Reddy's API business thrives on the deep technical strengths established over the last 30+ years in the development and manufacture of complex APIs such as steroids, peptides, complex long chain molecules and highly potent APIs (HPAPIs / oncology drugs). This expertise is complemented by our prowess in intellectual property and regulatory affairs which helps us consistently meet and exceed regulatory standards. Dr. Reddy's Treprostinil Diolamine API is the outcome of the extensive expertise in R&D, IP, and Regulatory.

A key component in helping our customers be first to market is a responsive supply chain. We achieve this by making sure that all our facilities are operating efficiently and to the latest standards of quality, safety, and productivity. A strong interconnect between business and factories allows for a quick reaction to dynamic market changes, so that we can avert shortages and meet sudden surges in demand.